Our resources have been developed by an interdisciplinary team based on published evidence and expert opinion.

However, they should never be used as a substitute for clinical judgement. Providers are responsible for assessing the unique circumstances and needs of each case. Adherence to these guidelines will not ensure successful treatment in every situation.

Toolkit Quick Links:

Access 24/7 provider support lines

Any provider seeking support for treating patients with MAT may utilize these Substance Use lines.

California Substance Use Hotline:
CA providers only, service of CA Poison Control System & National Clinician Consultation Center
24 hours a day, 7 days a week.
Focused on rapid access to advice for acute care bup starts
(844) 326-2626

National Clinician Consultation Center Substance Use Warmline
M-F 6am-5pm PT. Voicemail 24 hours a day, 7 days a week.
Specialty addiction medicine consultation
(855) 300-3595

Toolkit Quick Links:

A Patient-Centered, Rapid Access Approach to Substance Use Disorder

GUIDE: Prioritize timely medication access, improve care effectiveness, and expand on a ‘low-threshold’ model

Acute Care Treatment of Alcohol Use Disorder

GUIDE: Guidance incorporating treatment for alcohol use disorder into emergency department and inpatient settings

Acute Pain Management in Emergency Department and Critical Care

PROTOCOL: Clinical acute pain management guide for EDs patients undergoing buprenorphine treatment for opioid use disorder

Acute Pain Management in Medical Surgical Units

PROTOCOL: Clinical acute pain management guides for MedSurg patients undergoing buprenorphine treatment for opioid use disorder

Alcohol Use Disorders Identification Test (AUDIT)

TOOL: The Alcohol Use Disorders Identification Test (AUDIT) is a 10-item screening tool to assess alcohol consumption, drinking behaviors, and alcohol-related problems

Blueprint for Hospital Opioid Use Disorder Treatment

TOOLKIT: Focuses on the implementation of hospital-based opioid use disorder treatment programs

Bup XR Sample Discharge Instructions

PATIENT MATERIALS: Sample discharge instructions to personalize, focus on extended release injectable buprenorphine

Buprenorphine and Pharmacy Frequently Asked Questions

FAQ: Pharmacy related questions on buprenorphine, prescribing, substance use navigators and prescription insurance questions

Buprenorphine Extended Release: What You Need to Know

PATIENT MATERIALS: For patients who are interested in extended release injectable buprenorphine

Buprenorphine Frequently Asked Questions

FAQ: Buprenorphine pharmacology and medications for opioid use disorder treatment

Buprenorphine Hospital Quick Start

PROTOCOL: Clinical guide for the treatment of acute withdrawal and opioid use disorder using buprenorphine in any setting

Buprenorphine Quick Start in Pregnancy

PROTOCOL: Clinical guide for pregnant patients with opioid use disorder in need of treatment in any setting

Buprenorphine Sample Discharge Instructions

PATIENT MATERIALS: Sample discharge instructions to personalize, focus on buprenorphine (also available in Spanish, Tagalog, Vietnamese, and traditional and simplified Chinese)

Buprenorphine: What You Need to Know

PATIENT MATERIALS: Information for patients about buprenorphine and what to anticipate upon starting (also available in Spanish, Tagalog, Vietnamese, and traditional and simplified Chinese)

California MAT Telehealth Providers

TOOL: MAT Telehealth providers in California

Care for Patients with Opioid Use Disorder Who Are in Custody

GUIDE: Evidence-based practices to treat patients in custody for opioid use disorder, opioid overdose, and opioid withdrawal

Caring for Youth with Substance Use Disorders

TOOL: Clinical guide for providers treating pediatric patients with substance use disorder, including considerations about consent

Clinical Considerations for Order Sets

GUIDE: Evidence-based sample order sets for prescribing buprenorphine in acute care settings

Clinical Opioid Withdrawal Score

TEMPLATE: Example Clinical Opioid Withdrawal Scale (COWS) for providers reference when identifying a patient in opioid withdrawal

Core Elements of Substance Use Disorder Treatment in Acute Care Settings

TOOL: The ideal model for providing care to people who use drugs in acute care settings

Culture of Care

NURSING RESOURCE: Nurse specific education addressing the culture of healthcare and people who use drugs

DATA 2000 X-Waiver for Buprenorphine Prescribing

GUIDE: Information on DATA 2000 X-waiver and buprenorphine prescribing

Decriminalization of Personal Use and Possession of Small Quantities of Drugs

PUBLIC POLICY POSITION: Policy statement advocating investing in public health strategies to address substance use disorder as a health issue.

Discharge Considerations for Nurses

NURSING RESOURCE: Key patient discharge topics to address for nurses who may not have a SUN on shift

Documentation Examples for Procedure Code G2213

SITE EXAMPLE: Example prescriber documentation for procedure code G2213

Drug Abuse Screening Test (DAST)

TOOL: Drug Abuse Screening Test (DAST-10) is a 10-item brief screening tool to assess drug use, excluding alcohol or tobacco use, in the past 12 months

Engagement of Emergency Medical Services

PROJECT: This is a collection of actionable EMS resources

Enhanced Care Practice: Precipitated Withdrawal 90-Minute Bundle

SITE EXAMPLE: Treatment guideline for the initial treatment of precipitated withdrawal

Epic Dot Phrases for Substance Use Navigators

CA BRIDGE – SITE EXAMPLE – Epic Dot Phrases for SUNs – December 2020 Download ...

Equity and Harm Reduction for Communities of Color

TOOL: Understanding the racist history of drug policy and advancing equity for communities of color

Example Order Sets

SITE EXAMPLE: Screenshots of example order sets used at Zuckerberg San Francisco General Hospital

Extended Release Buprenorphine

GUIDE: Provider focused information about extended release injectable buprenorphine

Gentle Buprenorphine Home Start

PATIENT MATERIALS: Buprenorphine home start for people with major medical issues or with lower opioid tolerance (also available in Spanish, Tagalog, Vietnamese, and traditional and simplified Chinese)

Guide to Naloxone Distribution

GUIDE: How to apply for and set up a naloxone distribution program

Guide to Translated Patient Materials

Patient materials are available in Spanish, Tagalog, Vietnamese, Chinese (traditional), and Chinese (simplified)

Harm Reduction Kit

SITE EXAMPLE: Itemized inventory for harm reduction safe injection kits

Harm Reduction Sample Discharge Instructions

PATIENT MATERIALS: Sample discharge instructions to personalize, focus on harm reduction (also available in Spanish, Tagalog, Vietnamese, and traditional and simplified Chinese)

Harm Reduction Strategies for the Hospital Setting

GUIDE: How to incorporate harm reduction strategies into the hospital setting

Harm Reduction Supplies Order Set

SITE EXAMPLE: Screenshots of example harm reduction Epic order sets used at Montefiore Medical Center

Hiring a Substance Use Navigator

GUIDE: Information and guidance about hiring a substance use navigator

Hospital Education

TOOL: Flyer for promoting your OUD treatment program within your hospital

How to Apply to Get Your X Waiver

Step-by-step instructions on how to get your X Waiver certification

How to Use Your New X-Waiver

TOOL: Education on starting and prescribing buprenorphine, buprenorphine FAQs, and provider resources

Insurance Details Related to the Treatment of Substance Use Disorder

GUIDE: Information about navigating insurance landscapes for substance use disorder treatment

MAT and Trauma-Informed Care in Pregnancy

FAQ: Information regarding MAT and trauma-informed care for pregnant patients

MAT Toolkit for Nurses

TOOLKIT: Nurse specific education focusing on emergency department-based MAT

Medication for Addiction Treatment Courses for CME Credit

GUIDE: Prioritize timely medication access, improve care effectiveness, and expand on a ‘low-threshold’ model

Medicines for Treating Opioid Use Disorder: What You Need to Know

PATIENT MATERIALS: Overview of medications used in MAT (also available in Spanish, Tagalog, Vietnamese, and traditional and simplified Chinese)

Methadone Hospital Quick Start

PROTOCOL: Clinical guide for methadone for opioid use disorder treatment in the acute care setting

Naloxone: What You Need to Know

PATIENT MATERIAL: Flyer to distribute to patients along with naloxone kits

Nurse Initiated Buprenorphine Hospital Quick Start

PROTOCOL: Nursing treatment protocol to be used in parallel with Bup Hospital Quick Start

Nurse Initiated Buprenorphine Sample Order Set

SITE EXAMPLE: Sample nursing order set for nurse initiated buprenorphine starts

Options for Post-Acute MAT Treatment

GUIDE: Information on community-based MAT treatment options

Options to Support Substance Use Navigators in Emergency Departments

REPORT: Different pathways for financial support for substance use navigators

Outpatient Treatment Options After Hospital MAT Initiation

REPORT: Ensure patients have ongoing treatment after hospital initiated MAT